Custom libraries
You define the scientific question. AKos designs the library and coordinates its synthesis through the most suitable partners.
From Screening Collections to Custom Libraries
Whether you need focused analogues or specialized chemical modalities, we coordinate library synthesis through our global partner network.
Our custom library process
From target definition to analytical delivery in four clear steps.
Define your objectives
Discuss your biological target, chemical space, screening strategy, library size, and project goals.
Library design
Our scientists define the selection strategy using structural diversity, scaffold analysis, physicochemical properties, biological relevance, or other project-specific criteria.
Partner selection & library synthesis
The most appropriate partner is selected based on chemistry requirements, timelines, and project complexity.
Delivery & documentation
The completed library is delivered together with the available analytical documentation and supporting information provided by our partners.
Beyond Standard Libraries
From focused screening sets to highly specialized compound libraries, our global synthesis partners support virtually every stage of modern drug discovery.
Library design expertise
Standard & Focused Libraries
Custom libraries built around your biological target, chemical series, or screening strategy.
Covalent Libraries
Specialized collections designed for inclusion-proximity and targeted protein modulation approaches.
Molecular Glue Libraries
Specialized collections designed for induced-proximity and targeted protein modulation approaches.
Bifunctional Molecules
Libraries of PROTACs, molecular glues, degraders, stabilizers, and other bifunctional chemical modalities.
Macrocycle Libraries
Macrocycle collections designed to explore challenging targets with improved selectivity and binding properties.
Peptide Libraries
Linear and cyclic peptide libraries for ligand discovery, PPI modulation, and biologically inspired screening.
Hit Expansion Libraries
Analogue libraries designed to explore chemical space around validated screening hits.
Lead Optimization Libraries
Focused compound series created to improve potency, selectivity, and drug-like properties.
Before You Start Your Library Project
Everything you need to know before requesting a custom compound library.
- What types of libraries can you build?
- We support libraries ranging from focused screening sets and lead optimization series to macrocycle, peptide, covalent, molecular glue, and bifunctional molecule libraries through our trusted synthesis partners.
- Can you design a library around my target or project?
- Yes. Libraries can be designed around biological targets, chemical series, screening data, therapeutic areas, or specific medicinal chemistry objectives.
- How many compounds can a library contain?
- Library size depends on your project goals and budget, ranging from small focused sets to large screening collections.
- Do you synthesize the libraries yourself?
- No. AKos coordinates library design, project management, and scientific oversight while synthesis is performed by carefully selected partner organizations.
- What documentation is provided?
- Libraries are delivered with the available analytical documentation, purity information, and supporting data provided by our synthesis partners.
Need Something Beyond Standard Libraries?
When existing collections aren't enough, we coordinate the design and synthesis of custom libraries through our trusted global partner network.